BizTalk Server is a middleware product from Microsoft that helps to connect various systems together. Let’s take an example: If you look at any modern organization it will run its operations using a variety of software products. SAP for their ERP needs, Salesforce for their CRM needs, Oracle for their Database needs, + tons of other home-grown system like HR, Finance, Web, Mobile etc.
source http://www.c-sharpcorner.com/article/a-beginners-guide-to-microsoft-biztalk-server/
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